Manara - Qatar Research Repository
Browse
1/1
2 files

Virus‐like particles for vaccination against cancer

journal contribution
submitted on 2024-07-07, 10:10 and posted on 2024-07-07, 10:11 authored by Mona O. Mohsen, Daniel E. Speiser, Alexander Knuth, Martin F. Bachmann

Active immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus‐like particle‐based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of several infectious diseases and expectedly preventing cervical cancer caused by human papilloma virus. In contrast to these broad successes of disease prevention, therapeutic cancer vaccines remain to demonstrate clinical benefit. Yet, several preclinical and clinical trials have revealed promising results and are paving the way for medical breakthroughs. This study reviews and discusses the recent preclinical development and clinical trials in this field.

Other Information

Published in: WIREs Nanomedicine and Nanobiotechnology
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1002/wnan.1579

Funding

Qatar National Research Fund (PDRA4‐0118‐18002), Development and exploration of a novel personalized breast-cancer vaccine based on virus-like particles by incorporating tumor- specific T-cell epitopes.

Krebsforschung Schweiz (KFS‐3971‐08‐2016, KFS‐4291‐08‐2017‐R).

History

Language

  • English

Publisher

Wiley

Publication Year

  • 2019

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Medical Corporation
  • National Center for Cancer Care and Research - HMC
  • Interim Translational Research Institute - HMC

Usage metrics

    National Center for Cancer Care and Research - HMC

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC