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Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

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submitted on 2023-09-20, 05:36 and posted on 2023-09-21, 09:04 authored by Laith J. Abu-Raddad, Hiam Chemaitelly, Joel A. Malek, Ayeda A. Ahmed, Yasmin A. Mohamoud, Shameem Younuskunju, Zaina Al Kanaani, Abdullatif Al Khal, Einas Al Kuwari, Adeel A. Butt, Peter Coyle, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul Rahim, Hadi M. Yassine, Mohamed G. Al Kuwari, Hamad Eid Al Romaihi, Mohamed H. Al-Thani, Roberto Bertollini

We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons.

Other Information

Published in: Infection, Genetics and Evolution
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1016/j.meegid.2020.104684

History

Language

  • English

Publisher

Elsevier

Publication Year

  • 2021

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License

Institution affiliated with

  • Weill Cornell Medicine - Qatar
  • Hamad Medical Corporation
  • Medical Education - HMC
  • Qatar University
  • Biomedical Research Center - QU
  • Qatar University Health - QU
  • College of Health Sciences - QU HEALTH
  • Primary Health Care Corporation
  • Ministry of Public Health - State of Qatar

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