submitted on 2024-11-26, 09:39 and posted on 2024-11-26, 09:39authored byAfra M. Elhassan, Arwa Alsaud, Mohamed A. Yassin, Mahmood Aldapt, Lubna Riaz, Firdous Ghori, Aiman Bin Ahmad, Mohammad Abdulla
Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms, characterized by persistent thrombocytosis, platelets >450,000/μL, and evident clonal abnormalities like JAK2 V617F, MPL, CALR mutation and not fulfilling WHO criteria for MDS, CML, PV, and IDA. Here we report a 24-year-old female who presented with headache and was found to have thrombocytosis with a platelet count of 2,141 × 103/μL, diagnosed as ET as per WHO criteria 2008; she required ICU admission and thrombocytapheresis with a favorable outcome.