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The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature

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submitted on 2025-05-19, 07:38 and posted on 2025-05-19, 07:39 authored by Abdulrahman Al‐Abdulmalek, Reem Al‐Suliman, Mohammad Abu‐Tineh, Mostafa Ali, Mohamed A. Yassin

The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hypothesis to explain the association. Therefore, we propose Nilotinib for the treatment of patients with such coexisting diseases. Further studies are warranted to reveal the dynamics between these conditions.

Other Information

Published in: Clinical Case Reports
License: http://creativecommons.org/licenses/by-nc/4.0/
See article on publisher's website: https://dx.doi.org/10.1002/ccr3.7087

Funding

Open Access funding provided by the Qatar National Library.

History

Language

  • English

Publisher

Wiley

Publication Year

  • 2023

License statement

This Item is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License

Institution affiliated with

  • Hamad Medical Corporation
  • National Center for Cancer Care and Research - HMC

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