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Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature

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submitted on 2024-03-04, 10:52 and posted on 2024-03-04, 10:53 authored by Reda R.H. Youssef, Amr Elmahdy, Samah Kohla, Feryal Ibrahim, Ahmed Saied Sabry, Amal Alobaidly, Nehal Saloum

Hepatosplenic γδ T-cell lymphoma (HSTCL) is a very rare peripheral T-cell lymphoma characterized by extranodal infiltration of mature malignant post-thymic T-lymphocytes into sinusoids of the liver and spleen without lymphadenopathy and significant cytopenias. It is an aggressive form of lymphoma, resistant to the conventional chemotherapy. We report a case of HSTCL in pregnancy. Because this condition is an extremely aggressive and rare entity, data from these cases can help confirm the most suitable treatment regimen and timing of initiation. The role of ultrasound and magnetic resonance imaging in the diagnosis has been discussed. HSTCL is a rare entity of T-cell lymphoma, uncommon in female patients and very rarely reported during pregnancy.

Other Information

Published in: Case Reports in Oncology
License: https://creativecommons.org/licenses/by-nc/4.0/
See article on publisher's website: https://dx.doi.org/10.1159/000504568

Funding

Open Access funding provided by the Qatar National Library.

History

Language

  • English

Publisher

Karger

Publication Year

  • 2019

License statement

This Item is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License

Institution affiliated with

  • Hamad Medical Corporation
  • Women's Wellness and Research Center - HMC

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    Hamad Medical Corporation

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