Manara - Qatar Research Repository
10.1007_s10597-019-00537-y.pdf (598.37 kB)

Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study

Download (598.37 kB)
journal contribution
posted on 2022-11-22, 21:13 authored by Samer Hammoudeh, Hawra Al Lawati, Suhaila Ghuloum, Huma Iram, Arij Yehya, Imen Becetti, Nora Al-fakhri, Hany Ghabrash, Mena Shehata, Nighat Ajmal, Iman Amro, Hira Safdar, Yassin Eltorki, Hassen Al-Amin

This study aimed to assess the differential effects of first-generation (FGA) and second-generation antipsychotics (SGA) on the prevalence of risk factors for metabolic syndrome among mentally ill patients in Qatar. We also wanted to check if there is proper adherence with the guidelines for prescribing antipsychotics and the monitoring of metabolic effects in this population. We collected the available retrospective data (socio-demographic, psychiatric, anthropometric, and metabolic measures) from the records of 439 patients maintained on antipsychotics. The majority were males, married, employed, having a psychotic disorder, and receiving SGA. Patients on SGA showed more obesity, higher BP, and more elevated triglycerides compared to those on FGA. The prevalence of the abnormal metabolic measures was high in this sample, but those on SGA showed a significantly higher prevalence of abnormal body mass index and BP. Obesity and hypertension were common in patients maintained on antipsychotics, especially those on SGA. Polypharmacy was common, and many metabolic measures were not monitored properly in those maintained on antipsychotics. More prospective studies with guided monitoring of the patients' clinical status and metabolic changes are needed to serve better this population of patients.

Other Information

Published in: Community Mental Health Journal
See article on publisher's website:



  • English


Springer Science and Business Media LLC

Publication Year

  • 2019

Institution affiliated with

  • Weill Cornell Medical College in Qatar

Usage metrics

    Manara - Qatar Research Repository



    Ref. manager