submitted on 2023-03-15, 08:02 and posted on 2023-03-16, 06:21authored byAhmad Al Bishawi, Hamad Abdel Hadi, Eman Elmekaty, Musaed Al Samawi, Arun Nair, Mohammed Abou Kamar, Muna Al Maslamani, Alaaeldin Abdelmajid
Remdesivir was the first antiviral agent to receive FDA authorization for severe COVID-19 management, which restricts its use with severe renal impairment due to concerns that active metabolites might accumulate, causing renal toxicities. With limited treatment options, available evidence on such patient groups is important to assess for future safety.