Manara - Qatar Research Repository
Browse
prevalence_of_neutropenia_among_adult_arabs_in.77.pdf (584.68 kB)

Prevalence of neutropenia among adult Arabs in Qatar: Relation to other hematological parameters and anthropometric data

Download (584.68 kB)
journal contribution
submitted on 2024-02-12, 05:51 and posted on 2024-02-12, 05:52 authored by Mohamed A. Yassin, Ashraf T. Soliman, Saloua M. Hmissi, Mohammad A.J. Abdulla, Maya Itani, Ans A. Alamami, Mahmood B. Aldapt, Aasir M. Suliman, Ezzeddin A. Ibrahim, Mouhand F.H. Mohamed, Waail Rozi, Shehab F. Mohamed, Prem Chandra, Abdulqadir J. Nashwan

Neutropenia ranges from a normal variant to life-threatening acquired and congenital disorders. This study aims at providing baseline information regarding the prevalence and spectrum of neutropenia in the Arab blood donors who are living in Qatar. This retrospective cohort study was conducted to review the data of healthy Arab individuals (≥18 years) who donated blood between January 1, 2015 to May 15, 2019. A complete blood count was performed using automated analyzers. The prevalence of neutropenia was 10.7%. The prevalence in females was 32% and in males, it was 6%. Absolute neutrophil count (ANC) below 1 × 109/L was detected in 10% of Arab females and 1.8 % of Arab males. In females, the neutropenic group had significantly lower hemoglobin (Hb) levels and higher red cell distribution width, and lower total white blood cells and lymphocyte counts (P < .001) compared to the group with ANC > 1.5 × 109/L. Significant correlations were found between the ANC and Hb (r = 0.33, P < .05) and ANC and total white blood cells (r = 0.45, P < .01). The prevalence of neutropenia is considerably high in Arab adult females compared to other ethnic groups. Besides the genetic constitution of Arabs, the lower Hb and higher red cell distribution width in females suggest that iron deficiency could contribute to the development of neutropenia.

Other Information

Published in: Medicine
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1097/md.0000000000030431

Funding

Open Access funding provided by the Qatar National Library.

History

Language

  • English

Publisher

Wolters Kluwer

Publication Year

  • 2022

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Medical Corporation
  • National Center for Cancer Care and Research - HMC
  • Hamad General Hospital - HMC
  • Medical Research Center - HMC
  • Hazm Mebaireek General Hospital - HMC

Usage metrics

    Hamad Medical Corporation

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC