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Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report

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submitted on 2025-08-05, 08:20 and posted on 2025-08-05, 08:21 authored by Mohammed Abdulgayoom, Mohammad S. Afana, Awni Alshurafa, Mohamed A. Yassin
<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. Encouragingly, no subsequent vaso‐occlusive crises occurred. However, the potential for infusion‐related adverse events warrants close supervision. Further research is necessary to explore its full benefits on priapism management.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccr3.8585" target="_blank">https://dx.doi.org/10.1002/ccr3.8585</a></p>

Funding

Open Access funding provided by the Qatar National Library.

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Language

  • English

Publisher

Wiley

Publication Year

  • 2024

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Medical Corporation
  • National Center for Cancer Care and Research - HMC

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