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Patterns of prescription of antipsychotics in Qatar

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submitted on 2024-07-04, 10:38 and posted on 2024-07-04, 13:36 authored by Sami Ouanes, Imen Becetti, Suhaila Ghuloum, Samer Hammoudeh, Mena Shehata, Hany Ghabrash, Areej Yehya, Hawra Al-Lawati, Nora Al-Fakhri, Huma Iram, Nighat Ajmal, Yassin Eltorki, Hassen Al-Amin

Objective

Even though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in comparison with the international guidelines, and to scrutinize the sociodemographic and clinical features associated with antipsychotic polypharmacy.

Methods

All the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry–Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.

Results

Our sample consisted of 537 individuals on antipsychotics (2/3 were male; mean age 33.8±10.2 years), prescribed for a psychotic disorder in 57%, a mood disorder in 9.3%, and various other diagnoses in 33.7%. About 55.9% received one antipsychotic, 29.6% received two antipsychotics, and 14.5% received more than two antipsychotics. Polypharmacy was associated with younger age (p = 0.025), being single (p<0.001), the diagnosis of a psychotic disorder (p<0.001), and previous admissions to psychiatry (p<0.001).

Conclusions

Antipsychotic polypharmacy appears to be quite common in Qatar, as it is the case in many other countries, in contrast with most international recommendations. Studies are needed to explore the reasons behind this disparity.

Other Information

Published in: PLOS ONE
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1371/journal.pone.0241986

Funding

Qatar National Research Fund (UREP 16-012-3-003), Biopsychosocial determinants of the outpatients presenting with psychotic disorders in Doha: A retrospective study.

History

Language

  • English

Publisher

Public Library of Science (PLoS)

Publication Year

  • 2020

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Weill Cornell Medicine - Qatar
  • Hamad Medical Corporation
  • Rumailah Hospital - HMC
  • Mental Health Service - HMC
  • Psychiatry Hospital - HMC

Methodology

All the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry–Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.

Geographic coverage

Qatar

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    Weill Cornell Medicine - Qatar

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