Management of Baló Concentric Sclerosis with rituximab: A case study with long-term follow-up

Background

Baló concentric sclerosis (BCS) is a rare demyelinating disorder that overlaps with other demyelinating diseases. BCS usually present in the context of multiple sclerosis (MS) or preceding typical MS. It rarely presents as an isolated lesion, . IV methyl prednisolone (IVMP) is the mainstay in the treatment with various outcomes. Maintenance therapy is still not clearly defined. Case presentation/case report: We present a case of isolated BCS that responded clinically and radiologically to long-term rituximab therapy.

Conclusion

A definite guideline for treating patient with BCS either with MS or as isolated entity is still controversial. Our case reflects a remarkable response to rituximab in achieving clinical and radiological longterm remission.

Other Information

Published in: Neuroimmunology Reports
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1016/j.nerep.2023.100177