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Management of Baló Concentric Sclerosis with rituximab: A case study with long-term follow-up

Version 2 2023-10-22, 07:22
Version 1 2023-08-24, 11:26
journal contribution
revised on 2023-10-22, 07:21 and posted on 2023-10-22, 07:22 authored by Lina Okar, Beatriz Canibano, Dirk Deleu

Background

Baló concentric sclerosis (BCS) is a rare demyelinating disorder that overlaps with other demyelinating diseases. BCS usually present in the context of multiple sclerosis (MS) or preceding typical MS. It rarely presents as an isolated lesion, . IV methyl prednisolone (IVMP) is the mainstay in the treatment with various outcomes. Maintenance therapy is still not clearly defined. Case presentation/case report: We present a case of isolated BCS that responded clinically and radiologically to long-term rituximab therapy.

Conclusion

A definite guideline for treating patient with BCS either with MS or as isolated entity is still controversial. Our case reflects a remarkable response to rituximab in achieving clinical and radiological longterm remission.

Other Information

Published in: Neuroimmunology Reports
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1016/j.nerep.2023.100177

Funding

Open Access funding provided by the Qatar National Library

History

Language

  • English

Publisher

Elsevier

Publication Year

  • 2023

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License

Institution affiliated with

  • Hamad Medical Corporation
  • Medical Education - HMC

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