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Leukocyte chemotactic factor 2–related amyloidosis presenting with severe jaundice and hepatic encephalopathy

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submitted on 2023-03-15, 08:02 and posted on 2023-03-16, 06:21 authored by Hussam Almasri, Almurtada Razok, Ahmed Badi, Muneera Almohannadi, Abdo Lutf, Mahir Petkar, Abdelnaser Elzouki

Amyloidosis is a well-known disease with various types and subtypes. One of the most recently identified types is leukocyte chemotactic factor 2 amyloidosis (LECT 2), which was found to be common in certain ethnic backgrounds. It is suggested that the diagnosis of this type is vital to prevent any therapy-related complications when it is erroneously diagnosed as AL amyloidosis. The clinical presentation is usually slowly progressive kidney disease and mild hepatic impairment. We report a case of LECT2 amyloidosis, which presented with severe painless cholestasis and hepatic encephalopathy alongside progressive kidney disease.

Other Information

Published in: Clinical Case Reports
License: http://creativecommons.org/licenses/by-nc-nd/4.0/
See article on publisher's website: http://dx.doi.org/10.1002/ccr3.5185

History

Language

  • English

Publisher

Wiley

Publication Year

  • 2021

Institution affiliated with

  • Hamad Medical Corporation

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