Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

<p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too-early dose intensification may have produced lamotrigine-induced blood dyscrasia.</p> </div><p></p><h2>Other Information</h2> <p> Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5136" target="_blank">http://dx.doi.org/10.1002/ccr3.5136</a></p>