submitted on 2023-03-15, 08:02 and posted on 2023-03-16, 06:20authored byMuhammad Salem, Ahmed El‐Bardissy
Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too-early dose intensification may have produced lamotrigine-induced blood dyscrasia.