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10.1002_ccr3.4649.pdf (667.47 kB)

Heterotopic pregnancy after a spontaneous conception a case report with a review of clinical, laboratory and imaging findings

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journal contribution
submitted on 2023-03-15, 08:01 and posted on 2023-03-16, 06:20 authored by Ahmed H. Abdelmonem, Gamal Sayed, Abd Elwahid Abugazia, Samah Kohla, Reda Youssef

Heterotopic pregnancy (HP) describes the simultaneous presence of two pregnancies at different implantation sites. Usually, one pregnancy is intrauterine and the other one is ectopic. The incidence of HP after assisted reproductive technologies reaches 1:3900, but is very rare after a spontaneous pregnancy, with a reported incidence of 1 to 30,000 pregnancies.

Due to its rarity, complex clinical picture, and laboratory findings, it is challenging to diagnose HP. We present a case of spontaneous HP diagnosed in the first trimester by ultrasound (US) and magnetic resonance imaging (MRI) and subsequently managed successfully. We present an analysis of the clinical and laboratory findings as well as imaging, including MRI that we used to diagnose the condition. Additionally, we performed a literature review.


HP is a very rare condition frequently faced in obstetrics, gynecology, and emergency departments that requires a high index of clinical suspicion. US remains the imaging modality of choice in diagnosing a HP, however, in some cases, an MRI with a reported safety in the first trimester, can be used to provide additional information over US.

Other Information

Published in: Clinical Case Reports
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  • English



Publication Year

  • 2021

Institution affiliated with

  • Hamad Medical Corporation
  • Weill Cornell Medical College in Qatar
  • Qatar University
  • Primary Health Care Corporation

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