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Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar

journal contribution
submitted on 2024-03-20, 09:55 and posted on 2024-03-20, 09:55 authored by Adeel A. Butt, Mylai D. Guerrero, Elenor B. Canlas, Husni Al-Dwairi, Abeir Bakhiet Mohammed Ali Alimam, Abdur Rehman Mohamad, Mohammed Thamer Ali, Nidal Ahmad Asaad, Ali Ahmed Sheikh Saleh Alkeldi, Mohammad Fawaz Saber Mohammad, Anil G. Thomas, Abdullatif Al-Khal, Muna Al-Maslamani, Abdul-Badi Abou-Samra

Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association with SARS-CoV-2 vaccination was determined by four independent trained reviewers using a modified WHO algorithm. Among 6,928,359 doses administered, 138 deaths occurred within 30 days of vaccination; eight had a high probability (1.15/1,000,000 doses), 15 had intermediate probability (2.38/1,000,000 doses), and 112 had low probability or no association with vaccination. The death rate among those with high probability of relationship to SARS-CoV-2 vaccination was 0.34/100,000 unique vaccine recipients, while death rate among those with either high or intermediate probability of relationship to SARS-CoV-2 vaccination was 0.98/100,000 unique vaccine recipients. In conclusion, deaths attributable to SARS-CoV-2 vaccination are extremely rare and lower than the overall crude mortality rate in Qatar.

Other Information

Published in: Nature Communications
License: https://creativecommons.org/licenses/by/4.0
See article on publisher's website: https://dx.doi.org/10.1038/s41467-022-35653-z

Funding

Open Access funding provided by the Qatar National Library.

History

Language

  • English

Publisher

Springer Nature

Publication Year

  • 2023

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Medical Corporation
  • Communicable Disease Center - HMC
  • Heart Hospital - HMC
  • Weill Cornell Medicine - Qatar

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