Manara - Qatar Research Repository
Browse

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

Download (185.39 kB)
journal contribution
submitted on 2024-06-30, 12:17 and posted on 2024-06-30, 12:17 authored by Salman M. Toor, Varun Sasidharan Nair, Eyad Elkord

The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. Numerous vaccines have been developed to protect against influenza infections. However, the efficacies of current influenza vaccines, which include cell-based vaccines, recombinant vaccines, inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV) have dropped in recent years and do not provide long-term viral defense. Moreover, the hemagglutination inhibition (HAI) titers are widely considered to correlate with protection against influenza; however, patients with high titers have also been infected by influenza, while others without titers were protected [2]. Therefore, there is a real need to explore novel candidates of vaccine development and decrease mortality rates.

Other Information

Published in: Vaccines
License: https://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.3390/vaccines8030376

History

Language

  • English

Publisher

MDPI

Publication Year

  • 2020

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Bin Khalifa University
  • Qatar Biomedical Research Institute - HBKU
  • Cancer Research Center - QBRI

Usage metrics

    Qatar Biomedical Research Institute - HBKU

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC