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Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders

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submitted on 2024-08-20, 05:37 and posted on 2024-08-20, 05:37 authored by Farhan Mohammad, Mohd. Farooq Shaikh, Yasir Ahmed Syed, Fadel Tissir

Neurodevelopmental and psychiatric disorders, which currently lack effective treatment strategies (Aishworiya et al., 2022), pose a significant challenge to worldwide public health systems (Kularatna et al., 2022). One of the core clinical phenotype associated with these disabling disorders are cognitive deficits, which is likely due to molecular mechanisms that affect long-term changes in synaptic development, function and plasticity (Parenti et al., 2020). Understanding these mechanisms are the crucial first step for addressing cognitive impairments associated with these complex neurological conditions (Kozubski et al., 2021). Toward this purpose, our Research Topic focuses on the intricate aspects of brain cognitive functions, including the role of specific proteins, therapeutic interventions, modulation of neuronal circuits, and the impact of molecular mechanisms on cognitive impairments.

Other Information

Published in: Frontiers in Molecular Neuroscience
License: https://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.3389/fnmol.2023.1239315

Funding

Qatar National Research Fund (UREP28-269-1-051), Exploring neuronal and non-neuronal defects associated with neurodevelopmental disorders.

Qatar National Research Fund (NPRP13S-0121-200130), A PRECISION MEDICINE APPROACH TO TARGET COLORECTAL CANCER.

Qatar National Research Fund (NPRP14S-0319-210075), A Precision Medicine Initiative To Target Paediatric Cerebral Palsy, A Movement Disorder.

Qatar National Research Fund (NPRP14S-0404-21014), Genesis, Progression and Recurrence of Glioblastoma: Role of the Diaphanous 3 gene.

History

Language

  • English

Publisher

Frontiers

Publication Year

  • 2023

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Bin Khalifa University
  • College of Health and Life Sciences - HBKU

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