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Complicated Neurotuberculosis with sinus venous thrombosis: A case-report

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submitted on 2023-10-12, 08:51 and posted on 2023-10-16, 10:01 authored by Yousra Ali, Yahia Imam, Hasan S. Ahmedullah, Naveed Akhtar, Saadat Kamran, Muna Al Maslmani, A. Latif Al Khal, Ahmed Own, Dirk Deleu

Introduction

Neurotuberculosis comprises around 6% of systemic tuberculosis. It targets a younger population, and it often leads to severe neurological complications or death.

Case report

We report a young gentleman with a clinically defined tuberculous meningitis (TBM) and multiple neurological complication associated with TBM occurring simultaneously. This includes hydrocephalus requiring a ventriculoperitoneal shunt, vasculitic infarcts, cranial nerve palsies, TB granuloma and cerebral venous thrombosis. The cerebrospinal fluid polymerase chain reaction for tuberculosis as well as cultures remained negative repeatedly. The patient was treated with anti-tuberculous medication in addition to steroids based on validated scoring systems suggestive of TBM and made a good recovery.

Conclusion

This report highlights the different complication seen with TBM and the importance of using clinical criteria to guide management plan particularly when cultures are negative.

Other Information

Published in: IDCases
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1016/j.idcr.2022.e01374

Funding

Open Access funding provided by the Qatar National Library

History

Language

  • English

Publisher

Elsevier

Publication Year

  • 2022

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License

Institution affiliated with

  • Hamad Medical Corporation
  • Neurosciences Institute - HMC
  • Communicable Disease Center - HMC
  • Weill Cornell Medicine - Qatar