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Challenges in the diagnosis of pulmonary mucormycosis in a diabetic with a review of literature

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submitted on 2023-10-26, 07:15 and posted on 2023-10-26, 09:05 authored by Muhammad Yousaf, Sarah Salameh, Irfan Ul Haq, Samir Alhyassat, Merlin Thomas, Aisha Hussain, Mohd Wani, Ehab Massad, Hamad Abdel Hadi, Hisham Abdul Sattar, Mansoor Hameed

Diabetes Mellitus appears to be the most common underlying condition associated with mucormycosis; a rare opportunistic fungal infection associated with high morbidity and mortality. Pulmonary mucormycosis may mimic pneumonia and thus pose challenges in achieving a timely diagnosis critical to successful outcomes. We present a case of a 65-year-old diabetic who presented with fever and haemoptysis that was managed as pneumonia. A bronchial alveolar lavage grew Rhizopus mould that was thought to be a contaminant as he responded well to antibiotics. He required another admission in 4 weeks due to worsening symptoms. Failure to respond to antibiotics and ongoing clinical and radiological deterioration led to a lobectomy that confirmed a diagnosis of pulmonary mucormycosis. He responded well to surgical resection and antifungal therapy with a complete recovery. Elusive clinical presentation and insensitive conventional diagnostic techniques may make the diagnosis of mucormycosis challenging. Our case reports highlight the issues involved in the diagnosis and management of pulmonary Mucormycosis mimicking as pneumonia.

Other Information

Published in: Respiratory Medicine Case Reports
License: http://creativecommons.org/licenses/by/4.0/
See article on publisher's website: https://dx.doi.org/10.1016/j.rmcr.2021.101474

Funding

Open Access funding provided by the Qatar National Library

History

Language

  • English

Publisher

Elsevier

Publication Year

  • 2021

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License

Institution affiliated with

  • Hamad Medical Corporation
  • Hazm Mebaireek General Hospital - HMC
  • Hamad General Hospital - HMC
  • Communicable Disease Center - HMC
  • Weill Cornell Medicine - Qatar

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