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A case of crescentic glomerulonephritis in a patient with COVID-19 infection

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submitted on 2024-03-21, 06:42 and posted on 2024-03-21, 06:42 authored by Mouhammad J. Alawad, Eihab A. Subahi, Haneen A. Al-Ani, Noheir M. Taha, Ijaz Kamal


Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which is not yet known, but an immune process is likely to be the trigger.

Patient concerns:

A 27-year-old man presented to our hospital with facial puffiness and lower-limb swelling.


Laboratory assessment revealed features of impaired kidney function with proteinuria and hematuria; COVID-19 polymerase chain reaction was positive, which was consistent with pauci-immune crescentic focal segmental glomerulonephritis.


After renal biopsy, the patient was started on methylprednisolone and rituximab. Due to worsening kidney parameters, he underwent intermittent hemodialysis as needed.


Kidney function tests partially improved; he was discharged on oral steroids with follow-up in the nephrology clinic to observe for the need for further hemodialysis.


We conducted a literature review of cases of glomerulonephritis associated with COVID-19 and described numerous types of glomerulonephritis. This report highlights the importance of recognizing emerging glomerulonephritis with COVID-19, the different pathological patterns of renal biopsies, and management interventions and responses.

Other Information

Published in: Medicine
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Open Access funding provided by the Qatar National Library.



  • English


Wolters Kluwer

Publication Year

  • 2022

License statement

This Item is licensed under the Creative Commons Attribution 4.0 International License.

Institution affiliated with

  • Hamad Medical Corporation